DEPARTMENT OF VETERINARY MICROBIOLOGY

Salient Achievements:

1. Live attenuated cell culture vaccine against sheep pox was developed using Karnal strain of sheep pox virus.
2. Vaccine for protection of poultry against salmonellosis and a process for preparing the same (Patents, US 6,605, 285 B2 (Aug, 12, 2003) and India-189049-96 (March, 01, 2001)
3. Autogenous vaccine against hydropericardium syndrome virus (fowl adenovirus) in broiler birds.
4. IgY based passive immunotherapy against hydropericardium syndrome virus (fowl adenovirus) in broiler birds.
5. Inactivated cell culture vaccine against hydropericardium syndrome virus (fowl adenovirus) in broiler birds.
6. Immune complex vaccine against hydropericardium syndrome virus (fowl adenovirus) in broiler birds.
7. Cell culture vaccine against Marek’s disease and Infectious bursal disease in poultry.
8. Serological and molecular diagnostic tests for goat pox and sheep pox in goat and sheep, Newcastle disease, Fowl pox, Inclusion body hepatitis/hydropericardium syndrome, Infectious bursal disease in poultry and parvovirus infection in dogs.
9. Congo red binding test for detection of pathogenicity of Escherichia coli strains in poultry.
10. A competitive ELISA test was developed for specific detection of antibodies to Haemorrhagic septicaemia in sera of cattle, pigs, sheep and goats.
11. Anatomical studies on the Nervous system of buffalo and goat.
12. To detect the presence of urea in adulterated/ synthetic milk, a strip test has been developed. The test is sensitive enough to detect urea at a concentration of 0.1% in milk in only one minute.
13. Immunodiagnostic tests like ELISA, rider immunoassay (RIA), coagglutination (COAT), counter current Immunoelectrophoresis (CIE), fluorescent antibody test (FAT) have been standardized and carried out for the diagnosis of Infectious diseases, viz. infectious bursal disease, canine parvovirus infection, new castle, rota virus infection and salmonellosis.
14. A Marek’s disease virus strain isolated locally from an apparently healthy bird was attenuated in chicken embryo fibroblast cell culture. The virus at its 20th passage level was used as a vaccine and the protection afforded was comparable to other available MD vaccines.
15. Salmonella Toxoid afford 100% protection in mice.
16. Congo red binding test for detection of pathogenecity of Escherichia coli strains in poultry developed.
17. Studies based on serotypes of E.coli and antibiotic sensitivity pattern in colibacillosis in poultry were determined.
18. Enterotoxin and four novel cytotoxins of Salmonella were purified and characterized.